Details for gene set INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING)[GSEA]

Table: GSEA Results Summary

Dataset	set04_transDMproB_versus_LMproB
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING)
Enrichment Score (ES)	0.63417697
Normalized Enrichment Score (NES)	2.0259018
Nominal p-value	0.0
FDR q-value	0.022021817
FWER p-Value	0.091

Fig 1: Enrichment plot: INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING)
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PSMB1	271	3.438	0.0765	Yes
2	PSMB6	406	3.058	0.1503	Yes
3	PSMB10	554	2.796	0.2164	Yes
4	PSMB9	1005	2.291	0.2529	Yes
5	STAT1	1094	2.226	0.3071	Yes
6	SOCS3	1416	2.021	0.3434	Yes
7	PSMB2	1796	1.824	0.3713	Yes
8	STAT5A	2045	1.709	0.4032	Yes
9	PSMB3	2090	1.688	0.4456	Yes
10	PSMA5	2104	1.682	0.4894	Yes
11	STAT5B	2139	1.667	0.5318	Yes
12	PSMB8	2176	1.657	0.5737	Yes
13	STAT4	2448	1.564	0.6006	Yes
14	PSMA3	2575	1.524	0.6342	Yes
15	PSMA4	3845	1.130	0.5958	No
16	PSMB5	3966	1.100	0.6185	No
17	PSMA6	4276	1.032	0.6292	No
18	PSMD2	4743	0.926	0.6287	No
19	PSMA2	6367	0.596	0.5572	No
20	PSMB4	7842	0.322	0.4865	No
21	STAT3	8430	0.220	0.4607	No
22	PSMA7	9241	0.077	0.4192	No
23	PSMB7	9486	0.035	0.4070	No
24	PSMA1	14534	-1.013	0.1623	No
25	STAT2	14544	-1.016	0.1888	No
26	PSMC1	15017	-1.140	0.1936	No

Fig 2: INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING): Random ES distribution
Gene set null distribution of ES for INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING)